Abstract: Elaborated here in the essay are the research and development of the TP-Ti-110 TP-G2(Ti)titanium alloy oil tubing with premium connection.According to the requirements for material properties of the P110 oil well pipe, the types and performances of the currently-used titanium alloys are investigated.As a result it is determined to use the new type TA31(Ti80)titanium alloy as the material of the TP-Ti-110 titanium alloy oil tubing.As per the design of application requirement of the titanium alloy oil tubing, and based on the buttress thread, the special air-tight premium connection TP-G2(Ti) is developed.Comprehensive evaluation tests are conducted to the TP-Ti-110 TP-G2(Ti) titanium alloy oil tubing with premium connection to identify its mechanical properties, over-length performance and corrosion resistance.The said oil tubing as developed is quite satisfactory to the application requirements for the highly-corrosive service environment of the Yuanba Natural Gas Field, and has been successfully used for first all downhole application.